Publications by authors named "M D Krengauz"
Acta Naturae
January 2024
Article Synopsis
- 5'-Noraristeromycin, a mixture of two enantiomers, has strong cytotoxic effects on leukemia cells, with different effectiveness across cell lines (Jurkat, K562, THP-1).
- In toxicity studies on white mice, the lethal dose (LD) of 5'-noraristeromycin was found to be around 63.2 mg/kg, with notable doses causing varying levels of acute toxicity.
- Administering this substance leads to systemic damage to the internal organs and tissues of the mice, indicating significant health risks at certain dosage levels.
