The Impact of Surgical Prehabilitation on Postoperative Patient Outcomes: A Systematic Review.

Introduction: Prehabilitation (preoperative rehabilitation) encompasses a range of patient health driven interventions with the potential to enhance surgical outcomes. This systematic review aims to assess the efficacy of prehabilitation on postoperative outcomes across surgical specialties, focusing on physical functionality and postoperative length of stay (LOS).

Methods: Medline, Embase, CINAHL Plus, Cochrane Library, Scopus, and Clinicaltrials.

Unlocking Medical Student Success: A Systematic Review and Meta-Analysis of Third-Party Resources Used for Medical Education and USMLE Board Preparation.

Unlabelled: An increase in third-party commercial resources targeted towards medical students has led to substantial changes in the way students prepare for medical assessments. A systematic review and meta-analysis was conducted to identify the third-party resources most used by medical students. A total of 1056 citations were screened with 19 full-text studies included.

Endovascular thrombectomy for acute ischemic stroke with primary occlusion of the anterior cerebral artery: A meta-analysis.

Background: Anterior cerebral artery (ACA) occlusions account for up to 4 % of all acute ischemic strokes and may lead to debilitating outcomes. While endovascular thrombectomy (EVT) is a well-established treatment for large vessel occlusions, its efficacy and safety for primary ACA occlusions remains unclear. This systematic review and meta-analysis aims to address this gap by evaluating the clinical outcomes, safety, and efficacy of EVT in the treatment for primary ACA occlusions.

CD70 CAR T cells secreting an anti-CD33/anti-CD3 dual targeting antibody overcome antigen heterogeneity in AML.

CD70 has emerged as a promising target in acute myeloid leukemia (AML), and we have previously demonstrated the potency of an optimized CD70-targeted ligand-based CAR. However, here, we identify in vivo CD70 antigen escape as a limitation of single antigen targeting. Combination targeting of CD70 and CD33 may overcome AML antigen heterogeneity.