Publications by authors named "M D Holzman"

Objectives: To determine whether the timing of acetabular fracture fixation through an anterior approach influences estimated and calculated perioperative blood loss.

Design: Retrospective cohort study.

Setting: Level 1 trauma center from 2013 to 2021.

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Article Synopsis
  • The REGAIN trial found that spinal and general anesthesia provide similar outcomes regarding ambulation and survival after hip fracture surgery.
  • In a secondary analysis, researchers compared pain levels, analgesic use, and patient satisfaction between the two anesthesia types.
  • Results indicated that spinal anesthesia led to more severe pain in the first 24 hours post-surgery and higher prescription analgesic use at 60 days, while patient satisfaction remained comparable across both groups.
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We present a case of polymicrobial sepsis with spp. complicated by purpura fulminans following a dog-bite in a 50-year-old-man with an extensive history of opioid use disorder. Generally, severe cases are thought to occur in patients with underlying immune deficiencies.

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The skeletal system derives from multiple embryonic sources whose derivatives must develop in coordination to produce an integrated whole. In particular, interactions across the lateral somitic frontier, where derivatives of the somites and lateral plate mesoderm come into contact, are important for proper development. Many questions remain about genetic control of this coordination, and embryological information is incomplete for some structures that incorporate the frontier, including the sternum.

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