Factors affecting fatigue progression in multiple sclerosis patients.

Fatigue is one of the most prevalent and disabling symptoms among patients with MS, but there is limited research investigating the longitudinal determinants of fatigue progression. This study aims to identify the sociodemographic, behavioral and clinical characteristics, and therapeutic regimens that are correlated with worsening fatigue over time in patients diagnosed with MS. This is a retrospective chart review of 483 patients.

Effect of Chromium Supplementation on Serum Levels of Inflammatory Mediators: An Updated Systematic Review and Meta-analysis on Randomized Clinical Trials.

Chromium has been recognized for its beneficial effects on inflammation reduction; therefore, we conducted a systematic review and meta-analysis to find the effect of chromium supplementation on serum levels of C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6) in subjects aged 18 years and older. Related articles were identified by searching databases such as the Cochrane Library, ClinicalTrials.gov, ISI Web of Science, Scopus, and PubMed up until Agust 2024.

LesionScanNet: dual-path convolutional neural network for acute appendicitis diagnosis.

Acute appendicitis is an abrupt inflammation of the appendix, which causes symptoms such as abdominal pain, vomiting, and fever. Computed tomography (CT) is a useful tool in accurate diagnosis of acute appendicitis; however, it causes challenges due to factors such as the anatomical structure of the colon and localization of the appendix in CT images. In this paper, a novel Convolutional Neural Network model, namely, LesionScanNet for the computer-aided detection of acute appendicitis has been proposed.

A Systematic Review of the Long-Term Outcomes of Surgical Versus Non-surgical Management for Types A3 and A4 Thoracolumbar Spinal Fractures With No Neurological Deficits.

Thoracolumbar spinal fractures remain a significant concern in the orthopedic and neurosurgical practice and have a risk of neurological deficits in patients. However, in the majority of the cases, the neurological status remains intact. Generally, conservative management is favored for fractures of low severity and the surgical option is reserved for severe fractures.