Publications by authors named "M D Dake"
Background: Chronic limb-threatening ischemia (CLTI) in patients with chronic kidney disease (CKD) has a high risk of poor outcomes. We aimed to compare the outcomes of lower extremity revascularization in patients with CLTI stratified by CKD severity in patients enrolled in the prospective, randomized Best Endovascular vs Best Surgical Therapy in Patients with CLTI (BEST-CLI) trial.
Methods: The BEST-CLI trial dataset was queried to categorize patients into three groups according to CKD stage.
Anaerobic bacteria and methanogenic archaea at municipal landfill dumping sites play a vital role in the landfill ecology, waste degradation, global warming and climate change. Although landfill works as a cheap way of solid waste management, unmanaged landfill plays a significant role in spreading pollutants and pathogens in natural ecosystems. The genera and are important groups of anaerobic microbes from a public and environmental health perspective.
View Article and Find Full Text PDFArticle Synopsis
- The Rapid Fluorescence Focus Inhibition Test (RFFIT) measures the potency of rabies monoclonal antibodies, but is time-consuming and requires specialized facilities and trained personnel.
- The World Health Organization has encouraged the development of alternative methods, leading to the creation of an In-vitro ELISA test that uses inactivated rabies vaccine to quantify antibody potency.
- This new ELISA test is validated for accuracy and sensitivity, easy to perform, cost-effective, and can be conducted without the need for specialized labs, providing results in just a few hours.
Article Synopsis
- The GORE® TAG® Thoracic Branch Endoprosthesis is the only FDA-approved device for treating specific thoracic aorta conditions, and this study focuses on the neurological outcomes, particularly strokes, following its use.
- A total of 238 patients were analyzed, revealing an overall stroke rate of 5.9% at 12 months, with aneurysm patients experiencing the highest incidence of disabling strokes.
- The study documented that 40% of strokes occurred within 30 days after the procedure, with both hemorrhagic and ischemic types reported, while later strokes were mainly ischemic.
Objective: Several observational studies have demonstrated an association between diabetes mellitus (DM) and above-ankle amputation after lower extremity revascularization (LER). However, data from prospective randomized trials is lacking. This analysis compares the outcomes of patients with and without DM enrolled in the Best Endovascular vs Best Surgical Therapy in patients with Chronic Limb-Threatening Ischemia (BEST-CLI) trial.
View Article and Find Full Text PDF