Publications by authors named "M D Cserhati"

A novel Gram-stain-positive, rod-shaped, endospore-forming bacterium with peritrichous flagella, designated as P96 was isolated from the surface of maize roots. Strain P96 grew optimally at 28 °C, pH 7.0.

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Aims: Ficolin 3 (FCN3) has the highest complement-activating capacity through the lectin pathway and is synthesized mainly in the liver and lung. Yet, its potential molecular mechanism in hepatocarcinogenesis is not fully understood.

Materials And Methods: The expression of FCN3 in hepatocellular carcinoma (HCC) tumor and non-tumor tissues was analyzed by RT-qPCR, Western blotting and immunofluorescence staining assays.

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Background: The incidence and mortality rates of hepatocellular carcinoma among Hispanic individuals in the United States are much higher than in non-Hispanic White people. We conducted multi-omics analyses to elucidate molecular alterations in hepatocellular carcinoma among Hispanic patients.

Methods: Paired tumor and adjacent nontumor samples were collected from 31 Hispanic hepatocellular carcinomas in South Texas for genomic, transcriptomic, proteomic, and metabolomic profiling.

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Salinization and sodification are serious and worldwide growing threats to healthy soil functions. Although plants developed a plethora of traits to cope with high salinity, soil bacteria are also essential players of the adaptation process. However, there is still lack of knowledge on how other biotic and abiotic factors, such as land use or different soil properties, affect the bacterial community structure of these soils.

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Article Synopsis
  • - The study investigates the heightened rates of hepatocellular carcinoma (HCC) among Hispanics in the U.S. by analyzing tumor and adjacent non-tumor samples from Hispanic patients in South Texas through comprehensive multi-omics approaches.
  • - Key findings include high mutation frequencies related to the Wnt/β-catenin pathway and the identification of HCC subtypes, where one subtype showed better survival rates associated with immune activity and lower liver function-related gene activity.
  • - The research aims to provide insights into specific molecular features and potential biomarkers for HCC among Hispanic patients, laying groundwork for improved therapeutic strategies.
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