Publications by authors named "M D Crespi"

Root developmental plasticity relies on transcriptional reprogramming, which largely depends on the activity of transcription factors (TFs). NF-YA2 and NF-YA10 (nuclear factor A2 and A10) are downregulated by the specific miRNA isoform miR169defg. Here, we analyzed the role of the Arabidopsis thaliana TF NF-YA10 in the regulation of lateral root (LR) development.

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Background: Recent papers report significant survival gain after liver resection in BCLC-B and -C HCC patients. The results of minimally invasive liver surgery (MILS) in such patients have not been widely investigated so far.

Methods: Data regarding patients undergoing MILS or open liver resection (OLR) for HCC staged BCLC -B and -C were extracted from the HERCOLES database.

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Plants thrive in dynamic environments by activating sophisticated molecular networks that fine-tune their responses to stress. A key component of these networks is gene regulation at multiple levels, including precursor messenger RNA (pre-mRNA) splicing, which shapes the transcriptome and proteome landscapes. Through the precise action of the spliceosome complex, noncoding introns are removed and coding exons are joined to produce spliced RNA transcripts.

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Background: Minimal access liver surgery (MALS) is considered superior to open liver resection (OLR) in reducing the perioperative risk in patients affected by hepatocellular carcinoma (HCC). No national-level comparisons exist based on procedure complexity. This study aims to compare postoperative complications, postoperative ascites (POA), and major complications (MC) between MALS and OLR.

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Article Synopsis
  • Global warming threatens crop yields, making it crucial to understand thermotolerance mechanisms in plants.
  • Several heat stress transcription factors (HSFs) regulate how plants respond to high temperatures, but the specific regulators of alternative splicing related to heat stress are still unclear.
  • In tomatoes, the splicing factors RS2Z35 and RS2Z36 play a key role in regulating HSFA2 splicing and influence nearly 50% of RNAs that undergo temperature-sensitive alternative splicing, suggesting that they help enhance plants' ability to cope with heat stress.
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