Publications by authors named "M D Catalina"
Background & Aims: Pre-emptive transjugular intrahepatic portosystemic shunt (TIPS) is the treatment of choice for high-risk acute variceal bleeding (AVB; i.e., Child-Turcotte-Pugh [CTP] B8-9+active bleeding/C10-13).
View Article and Find Full Text PDFBackground: Systemic lupus erythematosus (SLE) is known to be clinically heterogeneous. Previous efforts to characterize subsets of SLE patients based on gene expression analysis have not been reproduced because of small sample sizes or technical problems. The aim of this study was to develop a robust patient stratification system using gene expression profiling to characterize individual lupus patients.
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- TLR7 and TLR8 are receptors that help the immune system fight viral infections but can also contribute to autoimmune diseases like lupus when activated incorrectly.
- * Research indicates that inhibiting TLR7/8 can enhance the effectiveness of lower doses of glucocorticoids (GCs), a common treatment for autoimmune conditions, reducing potential side effects.
- * In studies, combining TLR7/8 inhibitors with GCs showed improved outcomes in inflammatory responses and in a lupus mouse model, highlighting a promising new treatment approach for autoimmune diseases.
Objective: Non-cirrhotic portal vein cavernoma (PVC) is a cause of portal hypertension (PH) frequently affecting women of childbearing age. Cavernous transformation of the portal vein is frequently associated with prothrombotic disorders and often entails multiple hemodynamic changes, porto-collateral shunt development and thrombopenia, all of which can affect the course of pregnancy. Our aim was to evaluate the risk of PH-related complications and pregnancy outcomes in patients with PVC.
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