Publications by authors named "M D Carson"
Introduction: Latinx individuals are disproportionately affected by alcohol use disorder (AUD). Understanding Latinx individuals' barriers and facilitators to reach AUD-related goals can help implement culturally and linguistically concordant interventions to improve alcohol-related outcomes.
Methods: We conducted semi-structured qualitative interviews with Latinx, Spanish-speaking men with AUD within 20 weeks of hospital discharge who were seen by an addiction consult team during hospitalization in an urban, safety-net hospital in San Francisco.
Objective: To describe demographics, causative pathogens, hospitalization, mortality, and antimicrobial resistance of bacterial bloodstream infections (BSIs) among beneficiaries in the global U.S. Military Health System (MHS), a single-provider healthcare system with 10-year longitudinal follow-up.
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- * The researchers found that dark microglia interact with blood vessels and synapses and engage in trogocytosis, meaning they take pieces of pre-synaptic axon terminals.
- * They discovered that dark microglia express specific proteins like CLEC7a, LPL, and TREM2, and that TREM2 is crucial for their function, indicating their important role in synaptic pruning and brain development.
Article Synopsis
- Infections are a major complication in burn patients, particularly among U.S. military personnel who sustained injuries in Iraq and Afghanistan from 2009 to 2014, with 18% of the studied patients developing infections.
- The most common initial infection was pneumonia, occurring within four days post-injury, while those with infections had more severe burns, longer time before surgical treatment, and higher rates of inhalation injury.
- The research indicates that military personnel with burn injuries face significant risks for serious infections, with a notable percentage suffering from multidrug-resistant Gram-negative bacteria and a concerning mortality rate among those with multiple infections.
The liver has a critical role in regulating host metabolism, immunity, detoxification, and homeostasis. Proper liver function is essential for host health, and dysregulation of hepatic signaling pathways can lead to the onset of disease. The Wnt/β-catenin signaling pathway is an important regulator of liver homeostasis and function.
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