Publications by authors named "M D Bottinelli"

(Mg) and (Ms) are regarded as the most important avian mycoplasma species for today's chicken and turkey farming industry from clinical and economical perspectives. Control strategies for Mg and Ms have become more efficient due to investments in mycoplasma research over the last 70 years. These investments have contributed to the further implementation of serological and molecular testing, the development of vaccines, and the improvement of antimicrobial treatment strategies.

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Mycoplasmas are known as the minimalist microorganisms in the microbes' world. Their minimalist nature makes them highly sensitive to the environmental conditions and limits their ability to survive for extended periods outside their animal host. Nevertheless, there are documented instances of mycoplasma transmission over significant distances and this phenomenon may be linked to relatively unexplored abilities of mycoplasmas, such as their capacity to synthesize biofilm-the predominant mode of bacterial growth in nature.

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Article Synopsis
  • * This study aimed to develop two new high-resolution genotyping assays: multiple-locus variable number of tandem-repeats analysis (MLVA) and core genome multi-locus sequence typing (cgMLST), to improve strain identification and epidemiological investigations.
  • * The new assays successfully identified distinct genotypes and sequence types among various M. iowae strains, showing congruent results and high discriminatory power, which supports their effectiveness for genetic analysis of this pathogen.
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  • Abnormal electrocardiograms (ECGs) are common in patients with acute non-traumatic brain injuries, even when they have no prior heart disease.
  • This review focuses on understanding new-onset ECG changes, how often they occur, and their potential implications for patient outcomes, particularly in cases of subarachnoid and intracranial hemorrhages.
  • The presence of ECG abnormalities may indicate worse outcomes and complications like neurogenic pulmonary edema and delayed cerebral ischemia, suggesting the need for careful monitoring in critical care settings.
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Mycoplasma gallisepticum (MG) is an important pathogen of the poultry industry able to cause chronic respiratory disease in chickens and infectious sinusitis in turkeys. Despite the application of biosecurity measures and the availability of vaccines for chickens, monitoring systems routinely applied for MG detection are still essential for infection control. Pathogen isolation is time-consuming and not suitable for rapid detection, albeit it is a compulsory step for genetic typing and antimicrobial susceptibility evaluation of single strains.

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