Publications by authors named "M D Arenas"
Background/objectives: Prostate cancer (PCa) is characterised by its progression to a metastatic and castration-resistant phase. Prostate tumour cells release small extracellular vesicles or exosomes which are taken up by target cells and can potentially facilitate tumour growth and metastasis. The present work studies the effect of exosomes from cell lines that are representative of the different stages of the disease on the tumoral phenotype of PC3 cells.
View Article and Find Full Text PDFBackground: Ageing often affects biomarker production. Yet, clinical/optimal thresholds to guide clinical decisions do not consider this. Serum albumin decreases with age, but hypoalbuminaemia is defined as serum albumin <4.
View Article and Find Full Text PDFHemodialysis (HD) is a treatment with a significant environmental impact. One dialysis cycle is equivalent to the daily consumption of 3.5-4 people, and the average annual electricity consumption of a center is equivalent to that of approximately 2.
View Article and Find Full Text PDFArticle Synopsis
- Despite clinical guidelines recommending lower use of central venous catheters (CVC), the prevalence remains high among patients undergoing hemodialysis, leading researchers to explore whether this is due to unavoidable circumstances or factors that can be addressed.
- A study involving 637 chronic hemodialysis patients from various centers in Spain sought to identify modifiable factors influencing CVC use, comparing demographics, vascular access types, and reasons patients had for not using arteriovenous fistulas (AVF).
- Results showed that 40% of the patients utilized CVCs, with major reasons for CVC use including patient refusal for surgery (often due to fear) and having initiated hemodialysis with a CVC, indicating that