Fibrous by-products, including defective or double cocoons, are obtained during silk processing. These cocoons primarily contain fibroin and sericin (SS) proteins along with minor amounts of wax and mineral salts. In conventional textile processes, SS is removed in the production of smooth, lustrous silk threads, and is typically discarded.
View Article and Find Full Text PDFDNA transposons have emerged as promising tools in both gene therapy and functional genomics. In particular, the Sleeping Beauty (SB) DNA transposon has advanced into clinical trials due to its ability to stably integrate DNA sequences of choice into eukaryotic genomes. The efficiency of the DNA transposon system depends on the interaction between the transposon DNA and the transposase enzyme that facilitates gene transfer.
View Article and Find Full Text PDFImportance: Neoadjuvant therapy (NT) is an increasingly used treatment strategy for patients with localized pancreatic ductal adenocarcinoma (PDAC). Little research has been conducted on cancer care delivery during NT, and the standards for optimal delivery of NT have not been defined.
Objective: To develop consensus best practices for delivering NT to patients with localized PDAC.
Due to the emergence of virulent Enterococcus cecorum (EC) in young broiler chicken flocks, the transmissibility of EC during late embryogenesis needs to be defined. The purpose of the present study was to develop a horizontal transmission model to simulate exposure to virulent EC during the hatching phase. In Exp 1, EC5, EC7, or EC11B (∼10 CFU/embryo) was administered to a subset of the embryos, deemed seeders, by in ovo injection into the amniotic cavity at day 19 of embryogenesis.
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