Publications by authors named "M D Alani"

Polycystic ovary syndrome (PCOS) is one of the most common and important polygenic endocrine disorders among women of reproductive-aged. Current treatments are mostly used only to control the signs and symptoms of the disease, while not being able to completely prevent complications. Curcumin is one of the active compounds in turmeric, which is commonly used for a wide range of metabolic and inflammatory diseases.

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Background: Most trauma occurs among young male subjects in Qatar. We examined the predictive values of the delta shock index (DSI), defined as the change in the shock index (SI) value from the scene to the initial reading in the emergency unit (, subtracting the calculated SI at admission from SI at the scene), at a Level 1 trauma center.

Aim: To explore whether high DSI is associated with severe injuries, more interventions, and worse outcomes [, blood transfusion, exploratory laparotomy, ventilator-associated pneumonia, hospital length of stay (HLOS), and in-hospital mortality] in trauma patients.

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  • Transcatheter aortic valve replacement (TAVR) is a treatment for severe aortic stenosis, mainly affecting older adults, requiring accurate frailty assessments for optimal patient selection.* -
  • This study analyzed data from 14,000 patients at the University of Florida to improve frailty prediction for TAVR candidates by combining structured electronic health records and unstructured clinical notes, using advanced modeling techniques.* -
  • The integrated model significantly outperformed those using only electronic health record data, identifying key frailty predictors, which may enhance patient outcomes in TAVR procedures.*
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  • The study evaluated a clinical decision tool (CDT) for assessing thoracolumbar fractures in trauma patients, aiming to potentially replace traditional imaging methods to speed up the clearance of the TL spine.
  • Conducted on alert trauma patients with suspected injuries, the CDT tested for criteria like pain absence and movement capability to determine fracture presence.
  • Results showed the CDT had a high sensitivity (99.38%) for identifying the absence of fractures, but lower specificity (9.1%), indicating it was better at ruling out fractures than confirming them.
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In October 2018, the United Network for Organ Sharing changed their heart allocation criteria to prioritize patients on temporary mechanical circulatory support. This study assesses outcomes of patients bridged to orthotopic heart transplantation (OHT) with venoarterial extracorporeal membrane oxygenation (VA ECMO) since this change. We conducted a retrospective single-center study of adults (≥18 years) supported with VA ECMO at the time of OHT (October 1, 2018, to December 31, 2021).

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