Publications by authors named "M D'Ajello"

Thyroid gland tumors represent 1% of malignant tumors. In Italy their incidence is in constant growth. The aggressiveness depends on the histological type.

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Background And Objective: Nodular thyroid disease is very frequent in iodine-deficient areas affecting at least 50% of the population. Percutaneous laser ablation (LA) represents an effective method and an alternative to conventional surgery. Since the first description of the LA methodology for thyroid nodules, various studies have suggested some modifications to increase the percentage of volume reduction of the nodules.

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Thyroid surgery is a clean procedure and therefore antibiotic prophylaxis is not routinely recommended by most international guidelines. However, antibiotics are often used in clinical practice. We enrolled 2926 patients who performed a thyroid surgical operation between the years 2009 and 2011 in the 38 centers of endocrine surgery that joined the UEC--Italian Endocrine Surgery Units Association.

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Article Synopsis
  • The prevalence of nontoxic nodular goiter is common in adults, and surgical intervention is necessary when there is goiter growth, organ compression, or significant cosmetic issues.
  • Ultrasound-guided laser photocoagulation shows promise as a less invasive treatment for benign thyroid nodules, but studies indicate varying energy requirements for effective results.
  • A study with 40 patients demonstrated that effective thyroid nodule ablation requires delivering over 400-500 J/mL of energy, validating laser treatment as an alternative to traditional surgery but with potential side effects.
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Medullary thyroid carcinoma is a highly malignant and progressive disease. Surgery is the only effective treatment. Calcitonin is a significant marker for medullary thyroid carcinoma, and due to its sensitivity it represents a useful tool for the follow-up.

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