Experimental verification of halomethyl carbinol synthesis from carbonyl compounds using a TiCl-Mg bimetallic complex promoter.

A critical evaluation of the feasibility of a previously published method for synthesising halomethyl carbinols from carbonyl compounds and CHBr or CHCl using a bimetallic TiCl-Mg complex is presented. The synthesis of compounds lacking the -CH- group in their structure was achieved by following the procedures proposed in the reference literature or by introducing modifications to selected process parameters. These compounds were not identified as expected β-halohydrins but as products of reductive dimerisation or subsequent pinacolic rearrangement of carbonyl substrates.

Assessment of patient expectations toward health professionals and quality of life among Płock (Poland) residents aged 55 and over: a cohort study.

Background: The right attitude of health professionals (mainly doctors) towards patients-particularly older ones-determines patients' level of illness acceptance and quality of life. The aim of the study was to assess patient expectations of health professionals and quality of life among residents of Płock (Poland) aged 55 and over in relation to sociodemographic variables and to examine correlations between these patients' expectations and their quality of life.

Methods: The study included 2040 adults aged 55 and over, with 68.

microRNAs and Other Serological Markers of Liver Fibrosis in Patients with Alcohol-Related Liver Cirrhosis.

: It is essential to identify novel non-invasive markers of liver fibrosis for clinical and scientific purposes. Thus, the goal of our survey was to assess the serological expression of selected microRNAs (miRNAs) in patients with alcohol-related liver cirrhosis (ALC) and to correlate them with other existing markers. : Two hundred and thirty-nine persons were enrolled in the study: one hundred and thirty-nine with ALC and one hundred healthy controls.

Reaction to Disease and Coping Strategies in Stressful Situations among Psoriasis Patients: Cross-Sectional Study.

In the contemporary world, a cult of perfection is being created, and deviations from such an ideal image are becoming socially unacceptable. A particular situation arises when a defect or symptoms of a disease appear on the skin, which, in the case of people suffering from psoriasis, are a source of stress, dissatisfaction with the disease, and a reduction in quality of life. The aim of this study was to assess whether the quality of life related to the occurrence of psoriasis and the level of acceptance of the disease affect coping strategies in stressful situations.