Publications by authors named "M Cwynar"
Background: The cardio-ankle vascular index (CAVI) measure of arterial stiffness is associated with prevalent cardiovascular risk factors, while its predictive value for cardiovascular events remains to be established. The aim was to determine associations of CAVI with cardiovascular morbimortality (primary outcome) and all-cause mortality (secondary outcome), and to establish the determinants of CAVI progression.
Methods: TRIPLE-A-Stiffness, an international multicentre prospective longitudinal study, enrolled >2000 subjects ≥40 years old at 32 centres from 18 European countries.
Article Synopsis
- Acute genital ulcers can present in females of any age, particularly as an emergency in children, causing diagnostic challenges for healthcare professionals like pediatricians and gynecologists.
- A detailed medical history is crucial, as past conditions and vaccinations may contribute to acute genital ulcers, including new agents such as COVID-19.
- A case study of a 12-year-old girl with ulcers revealed accompanying symptoms like abdominal pain and fever, with abnormal blood tests indicating inflammation while common infection tests returned negative, alongside a history of autoimmune disease.
Background: Numerous studies based on assessment of lithium clearance demonstrated higher sodium reabsorption in renal proximal tubules in individuals with hypertension, overweight, obesity, metabolic syndrome, or diabetes.
Aims: We aimed to assess the influence of angiotensin-converting enzyme inhibitors (ACE-I) or angiotensin-II-receptor antagonists (ARB) treatment on sodium handling.
Methods: In a sample of 351Caucasian subjects without diuretic treatment with prevailing sodium consumption, we studied associations between renal sodium reabsorption in proximal (FPRNa) and distal (FDRNa) tubules assessed by endogenous lithium clearance and daily sodium intake measured by 24-hour excretion of sodium (UNaV), in the context of obesity and long-term treatment with ACE-I or ARB.