Publications by authors named "M Cristina Negri"
Background: Intracochlear schwannomas (ICSs) are a subtype of intralabyrinthine schwannomas, completely located in the cochlear lumen. ICSs are particularly rare in the pediatric population. Putative diagnosis is made on the basis of magnetic resonance findings with signal characteristics that should remain the same at follow-up imaging.
View Article and Find Full Text PDFArticle Synopsis
- The text discusses the perceived obsolescence of external hemipelvectomies due to societal views on amputations as therapeutic failures and associated risks, alongside a review of scientific literature.
- Two case studies highlight distinct patient outcomes: an 18-year-old who had a successful recovery and a 71-year-old who faced severe complications and died shortly after surgery.
- The study concludes that external hemipelvectomies, though complex, may still be relevant for specific cases when carefully evaluated by multidisciplinary teams and with informed consent from patients.
Synergistic potential of Bauhinia holophylla leaf extracts with conventional antifungals in the inhibition of Candida albicans: A new approach for the treatment of oral candidiasis.
Arch Oral Biol
November 2024
Objective: This study investigated the combination of Bauhinia holophylla (Bong.) Steud. leaf extracts with conventional antifungal agents, highlighting the extracts' potential as adjuvants in treating oral candidiasis.
View Article and Find Full Text PDFPurpose: Endocrine-disrupting compounds, including bisphenol A (BPA), may promote obesity influencing basal metabolic rate and shifting metabolism towards energy storage. The role of 1,25‑Dihydroxyvitamin D3 (VitD) in counteracting adipogenesis is still a matter of debate. Thus, the current study aims to investigate whether and how VitD exposure during adipogenesis could prevent the pro-adipogenic effect of BPA in two adipocyte models, mouse 3T3-L1 cell line and human adipose-derived mesenchymal stem cells (hAMSC).
View Article and Find Full Text PDFCochlear implants for hereditary ATTR amyloidosis: a case report of two cases.
Eur Arch Otorhinolaryngol
August 2024
Purpose: To analyze the clinical presentation, management, and outcome of two sisters affected by hereditary transthyretin related amyloidosis (ATTRv) and bilateral severe-to-profound hearing loss treated with cochlear implant.
Methods: A description of two patients underwent three cochlear implant (CI) surgery was performed. Age at time of implantation ranged from 48 to 53 years.