Publications by authors named "M Craig Caldwell"

Bovine respiratory disease (BRD) is one of the most common economic and health challenges to the beef cattle industry. Prophylactic use of antimicrobial drugs can alter the microbial communities in the respiratory tract. Considering that the bovine upper respiratory tract microbiome has been associated with generalized health, understanding the microenvironment that influences this microbiome may provide insights into the pathogenesis of BRD.

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With no effective treatments for functional recovery after injury, spinal cord injury (SCI) remains one of the unresolved healthcare challenges. Human induced pluripotent stem cell (hiPSC) transplantation is a versatile patient-specific regenerative approach for functional recovery after SCI. Injectable electroconductive hydrogel (ECH) can further enhance the cell transplantation efficacy through a minimally invasive manner as well as recapitulate the native bioelectrical microenvironment of neural tissue.

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Article Synopsis
  • Xenodens calminechari is a mosasaurid species named from a questionable fossil specimen, suggesting the possibility of forgery due to its non-scientific collection method.
  • The teeth in the specimen's maxilla appear to be artificially placed, leading to concerns about the validity of its defining features.
  • The paper highlights broader issues in paleontology regarding poorly tested commercial specimens and the complexities of dental variations in reptiles, ultimately questioning the legitimacy of the Xenodens calminechari classification.
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Article Synopsis
  • This protocol outlines a Cochrane Review focused on the timing of vitrectomy following open-globe injuries.
  • The main goal is to compare the effects of performing the surgery early versus later on patients' visual outcomes.
  • The review aims to provide evidence that could guide clinical decisions regarding the optimal timing for vitrectomy in such cases.
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Platelet activation plays an essential role in clot formation to prevent blood loss following vascular damage. In pathologic conditions, platelet activation can lead to obstructive clots, disrupting blood flow and resulting in thrombosis. Native Americans suffer disproportionately from arterial disease and previous research has shown that Blacks are enriched in genetic polymorphisms that correlate with higher platelet reactivity contributing to an increased risk for thrombosis.

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