Publications by authors named "M Cotte"

Article Synopsis
  • Tau protein is key in various neurological disorders, but the mechanisms of its progression and spread in the brain remain unclear due to difficulties in analyzing tau aggregates.
  • Using advanced techniques like micro-x-ray diffraction (µXRD) and micro-X-ray fluorescence (μXRF), researchers studied tau lesions in a 79-year-old male with dementia, revealing distinct forms of tau and their locations in the brain.
  • Findings indicated that different types of tau lesions had unique chemical environments, affecting their structure and spread, with higher fibrillar tau density linked to greater sulfur deposition and the presence of metals like zinc and calcium in all tau lesions.
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Article Synopsis
  • Lead-calcium phosphates, specifically the (PbCa)(PO)OH solid solution, are valuable materials found in cultural heritage artifacts, yet their diagnostic properties have been under-studied.
  • This paper investigates the relationship between the composition and structure of these compounds, aiming to establish key markers for their identification in cultural heritage samples using non-destructive methods.
  • The researchers used advanced techniques like scanning electron microscopy and synchrotron radiation-based X-ray methods to analyze variations in these materials, providing useful data and methods for future studies in the field.
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Article Synopsis
  • The study aimed to compare dislocation and complication rates between dual-mobility (DMC) and single-mobility (SM) acetabular components in primary total hip arthroplasties (THAs) performed from 2010 to 2019.!
  • A total of 1,940 THAs were analyzed, revealing significantly fewer dislocations in the DMC group (0.17%) compared to the SM group (1%), but no significant difference in overall complications or revision rates between the two groups.!
  • The findings suggest that DMCs are beneficial in reducing dislocation risk in high-risk patients, with both DMC and SM showing similar long-term survival rates for the acetabular components.
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Article Synopsis
  • - Analyzed a microsample from Leonardo da Vinci's artwork using advanced techniques, revealing a unique blend of oil mixed with lead pigment components including plumbonacrite, which indicates an alkaline environment.
  • - The composition suggests that Leonardo aimed to create a thick paint for a wooden panel by using a high amount of lead II oxide (PbO), although sources in his manuscripts about PbO are unclear.
  • - Further analysis shows that Leonardo's palette included not just PbO but also other lead compounds like litharge and massicot, along with newly identified phases in historical painting like shannonite.
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This paper accounts for the diagnostic campaign aimed at understanding the phenomenon of black stains appeared on the passepartout close to the margins of Folio 843 of Leonardo da Vinci's Codex Atlanticus. Previous studies excluded microbiological deterioration processes. The study is based on a multi-analytical approach, including non-invasive imaging measurements of the folio, micro-imaging and synchrotron spectroscopy investigations of passepartout fragments at different magnifications and spectral ranges.

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