Publications by authors named "M Cortina"
Purpose: To report the indications, postoperative visual outcomes, and long-term graft survival of primary pediatric keratoplasties performed at a single tertiary care center.
Methods: We conducted a retrospective review of pediatric patients (16 years and younger) who underwent surgical intervention for corneal opacity at a tertiary care center to evaluate long-term graft survival and visual rehabilitation.
Results: Seventy-three eyes of 46 patients met inclusion criteria.
Purpose: The purpose of this study was to characterize the morphological and immunological aspects of biointegration at the optic-cornea joint of a second-generation synthetic corneal device.
Methods: The initial prototype, single-piece optic-skirt configuration, is constructed from compact and flexible perfluoroalkoxy alkane with porous expanded polytetrafluoroethylene (ePTFE) overlying the skirt to allow skirt-cornea biointegration. The second-generation version was modified to add ePTFE around the optic wall to allow optic-cornea biointegration.
Purpose: To investigate healthcare disparities associated with keratoconus (KCN) patients receiving treatment (corneal cross-linking [CXL] and keratoplasty), as well as comorbidities associated with KCN.
Design: Retrospective clinical cohort study.
Methods: A total of 3224 patients from the University of Illinois Hospital & Health Sciences System (UI-Health) database from 2020 to 2024 were examined, including 1612 patients with an International Classification of Diseases, Tenth Revision diagnosis of KCN, and 1612 ophthalmology patients as a control group.
Objective: To evaluate the published literature on the efficacy of amniotic membrane grafting (AMG) in the management of acute chemical and thermal ocular surface burns with respect to the rate of corneal re-epithelialization and improvement of visual acuity or corneal clarity.
Methods: Literature searches were conducted in the PubMed database in May 2023 and updated in January 2024 and were limited to the English language without date restrictions. The searches yielded 474 citations; 58 were reviewed in full text, and 9 met the inclusion criteria.
Article Synopsis
- The text reviews the safety and effectiveness of epithelium-off corneal collagen cross-linking (CXL) as a treatment for progressive corneal ectasia, specifically keratoconus (KCN) and ectasia after refractive surgery.
- A comprehensive literature search led to the inclusion of 6 high-quality randomized clinical trials, all showing positive outcomes, including decreased progression rates and improved visual acuity in patients undergoing treatment compared to controls.
- The findings indicate that epithelium-off CXL is effective in managing KCN and post-refractive surgery ectasia with a low incidence of complications, suggesting a favorable safety profile.