Impact of malnutrition and nutrition support in hospitalised patients with inflammatory bowel disease.

Background: Malnutrition is prevalent in patients with inflammatory bowel disease (IBD) and has been associated with worse clinical outcomes.

Aims: This observational study examines trends in protein-calorie malnutrition (PCM) amongst hospitalised IBD and non-IBD patients, and the association between (1) malnutrition and (2) nutrition support and hospitalisation outcomes.

Methods: We queried the Nationwide Readmissions Database from 2010 to 2018 for hospitalisations with and without IBD.

Analysis of milk production and greenhouse gas emissions as a function of extreme variations in forage production among French dairy farms.

Many studies that investigate mitigation strategies of greenhouse-gas (GHG) emissions from farming systems often build farm typologies from average data from multiple farms. Results from farm typologies are useful for general purposes but fail to represent variability in farm characteristics due to management practices or climate conditions, particularly when considering consequences of extreme environmental events. This limitation raises the issue of better distinguishing, within datasets of farms, farms that have average characteristics from those that deviate from average trends, in order to improve assessment of how climate variability influences farm performance.

Contribution of LCA to decision making: A scenario analysis in territorial agricultural production systems.

Territorial Life Cycle Assessment (TLCA) appears a promising method to support informed decision making of local actors in territorial agricultural production systems (TAPS), by assessing environmental impacts of agricultural activities and potential strategies. The objectives of this study were to i) adapt TLCA methodology to integrated environmental assessment of TAPS and ii) evaluate TLCA's contribution to supporting informed decision making by assessing scenarios of change in TAPS. A TLCA of the agricultural sector was performed for a territory in the Aube department in France, including main crops and animal production types from raw material extraction to the first stage of processing.

The IBD-associated long noncoding RNA regulates the balance between inflammatory and anti-inflammatory cytokine production after T-cell stimulation.

The inflammatory bowel diseases (IBD) are a complex set of chronic gastrointestinal inflammatory conditions arising from the interplay of genetic and environmental factors. This study focuses on noncoding RNA transcripts as potential mediators of IBD pathophysiology. One particular gene, interferon γ-antisense 1 (), has been consistently observed to be elevated in the intestinal mucosa of patients with actively inflamed IBD versus healthy controls.

Hepatitis C Virus Treatment in Patients With Chronic Kidney Disease and in Kidney Transplant Recipients.

An important interplay exists between hepatitis C virus (HCV) infection and chronic kidney disease (CKD). HCV infection is associated with an increased risk of morbidity and mortality in patients coinfected with CKD, and patients with CKD have an increased risk of HCV infection. Direct-acting antiviral (DAA) agents have changed the landscape of treatment with excellent sustained virologic response rates and fewer side effects than previously seen.