Publications by authors named "M Cornaggia"
Urinary microbial diversities have been reported in humans according to sex, age and clinical status, including painful bladder syndrome/interstitial cystitis (PBS/IC). To date, the role of the urinary microbiome in the pathogenesis of PBS/IC is debated. Feline idiopathic cystitis (FIC) is a chronic lower urinary tract disorder affecting cats with similarities to PBS/IC in women and represents an important problem in veterinary medicine as its aetiology is currently unknown.
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- Antibiotic usage can lead to the spread of antibiotic resistance genes (ARGs) in microbial communities, raising public health concerns due to the potential transmission among pathogens.
- The origins and transmission routes of these ARGs, particularly from farms where antibiotics are used in animal husbandry, are still unclear, although studies indicate dairy farms are hotspots for high-risk ARGs.
- The research highlights calves as significant contributors to ARG spread in dairy farms and suggests focused strategies to reduce ARG levels in this area of livestock production.
Article Synopsis
- In November 2020, a hatchery in Northern Italy experienced a significant 30% mortality rate in juvenile Siberian and Russian sturgeons and their hybrids, showing symptoms like bloating and abnormal swimming patterns.
- Necropsy and histological examinations revealed serious gastrointestinal issues, particularly necrosis of the intestinal lining, along with an overgrowth of Clostridium perfringens bacteria.
- An increase in feeding from 0.4% to 1.5% of body weight per day successfully halted the mortality after five days, suggesting that proper nutrition restored the normal balance of intestinal microbiota.
The incidence of chronic idiopathic inflammatory bowel diseases (IBD) is growing in western countries, making their histological diagnosis an everyday task for all pathologists. Reviews from the literature strongly suggest that such diagnosis cannot be performed on the histological ground alone but requires a clinical-pathological approach. Moreover, bewildering variations can be observed in the terminology employed to report either individual lesions or diagnostic categories.
View Article and Find Full Text PDFBackground/aims: In order to better define the evolutive potentiality of non-invasive neoplasia (formerly dysplasia) a study of the cytological differentiation and of the behavior of p53 in relation to the clinical progress has been performed.
Methodology: Gastro-entero-pancreatic antigens, p53 and Ki-67 expression were evaluated in 120 cases of epithelial gastric dysplasia: 70 cases of low-grade dysplasia (LGD) and 50 cases of high-grade dysplasia (HGD). For the cytological study four antigens were studied: two of them gastric (pepsinogen C, gastric foveolar M1), one enteric (CAR-5) and one pancreatic (DU-PAN-2).