Publications by authors named "M Cormican"
Paratyphoid B fever (PTB) is caused by an invasive lineage (phylogroup 1, PG1) of Salmonella enterica serotype Paratyphi B (SPB). However, little was known about the global population structure, geographic distribution, and evolution of this pathogen. Here, we report a whole-genome analysis of 568 historical and contemporary SPB PG1 isolates, obtained globally, between 1898 and 2021.
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- Carbapenemase-producing Enterobacterales (CPE) are multidrug-resistant bacteria that can spread their resistance genes via mobile genetic elements, complicating infection control efforts.
- A study in Galway, Ireland involved whole-genome sequencing of CPE samples from patients and wastewater to understand the distribution and characteristics of these organisms and their resistance genes.
- Findings revealed that most resistance genes were found on plasmids, with specific plasmid types associated with different CPE strains, highlighting the genetic mechanisms facilitating the spread of resistance between humans and the environment.
Article Synopsis
- * A total of 18 carbapenemase variants were identified, predominantly in ST131 clades A and C, with the most common variants being detected in 14 and 12 countries, respectively.
- * The rise in isolates carrying these genes since 2021 highlights a significant public health threat posed by the high-risk ST131 lineage.
BackgroundThe war in Ukraine led to migration of Ukrainian people. Early 2022, several European national surveillance systems detected multidrug-resistant (MDR) bacteria related to Ukrainian patients.AimTo investigate the genomic epidemiology of New Delhi metallo-β-lactamase (NDM)-producing from Ukrainian patients among European countries.
View Article and Find Full Text PDFThe major determinant of blood culture (BC) diagnostic performance is blood volume, and pediatric sample volumes are frequently low. We aimed to assess BC volumes in our institution, design an intervention to increase volumes, and assess its impact. All pediatric BCs submitted over a 7-month period to the microbiology laboratory in a university hospital (including emergency department, pediatric ward, and neonatal unit) were included.
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