Publications by authors named "M Contrini"

Article Synopsis
  • Bartonella henselae is the bacteria behind cat scratch disease (CSD), which usually causes swollen lymph nodes but can sometimes lead to serious complications; this study aimed to analyze differences in clinical features between systemic and localized cases in children.
  • The study reviewed medical records from a pediatric hospital in Buenos Aires, identifying 197 CSD patients, predominantly aged 8 years, with common symptoms being fever and lymphadenopathy; systemic involvement occurred in 34.5% of cases, often presenting as abscesses in organs like the spleen and liver.
  • Findings indicated that patients with systemic diseases exhibited higher rates of fever and elevated C-reactive protein levels; nearly all patients received antibiotic
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Background: Humoral immune response against the pre-fusion (pre-F) conformation of respiratory syncytial virus (RSV) F protein has been proposed to play a protective role against infection. An RSV pre-F maternal vaccine has been recently approved in several countries to protect young infants against RSV. We aimed to assess serum IgG titers against the pre-F and post-F conformations of RSV F protein and their association with life-threatening RSV disease (LTD) in previously healthy infants.

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Numerous factors can increase the risk of severe influenza; however, a majority of severe cases occur in previously healthy children. Identification of high-risk children is important for targeted preventive interventions and prompt treatment. The aim of this study was to evaluate MUC5AC as a biomarker for influenza disease severity in children.

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Article Synopsis
  • Zika virus (ZIKV) infection in Orán, Argentina, was studied to compare its clinical presentation with dengue virus (DENV) infection, revealing that ZIKV generally presents milder symptoms, though rash and itching are more common.
  • A retrospective analysis was conducted at San Vicente de Paul Hospital from 2016 to 2018, evaluating 63 ZIKV patients regarding clinical features, viral load, and immune responses, and highlighting a notable increase in cases among females and milder symptoms in younger patients.
  • The findings indicate significant overlap in clinical presentations between ZIKV and DENV, complicating diagnosis and risk assessments, especially for vulnerable populations.
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Background: Coronavirus disease 2019 (COVID-19) is usually mild and self-limited in children. However, a few Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infections in children may progress to severe disease with respiratory distress or can result in a multisystem inflammatory syndrome (MIS-C) associated with COVID-19. The immune mechanisms for these differential clinical outcomes are largely unknown.

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