Management of severe BK viremia in a patient receiving a kidney transplant from a hepatitis C virus-positive donor: A case report.

Purpose: A case of BK nephropathy in a kidney transplant recipient who received an organ from a hepatitis C virus (HCV)-positive donor is reported.

Summary: A 66-year-old male negative for HCV with chronic kidney disease secondary to diabetic glomerulosclerosis received a kidney transplant from an HCV-viremic donor. His initial postoperative course was uncomplicated, and HCV treatment with glecaprevir/pibrentasvir was initiated after discharge.

Propagation of Disturbances in AC Electricity Grids.

The energy transition towards high shares of renewable energy will affect the stability of electricity grids in many ways. Here, we aim to study its impact on propagation of disturbances by solving nonlinear swing equations describing coupled rotating masses of synchronous generators and motors on different grid topologies. We consider a tree, a square grid and as a real grid topology, the german transmission grid.

Capillary channel flow experiments aboard the International Space Station.

In the near-weightless environment of orbiting spacecraft capillary forces dominate interfacial flow phenomena over unearthly large length scales. In current experiments aboard the International Space Station, partially open channels are being investigated to determine critical flow rate-limiting conditions above which the free surface collapses ingesting bubbles. Without the natural passive phase separating qualities of buoyancy, such ingested bubbles can in turn wreak havoc on the fluid transport systems of spacecraft.

Antinociceptive effect of peripheral serotonin 5-HT2B receptor activation on neuropathic pain.

Serotonin is critically involved in neuropathic pain. However, its role is far from being understood owing to the number of cellular targets and receptor subtypes involved. In a rat model of neuropathic pain evoked by chronic constriction injury (CCI) of the sciatic nerve, we studied the role of 5-HT(2B) receptor in dorsal root ganglia (DRG) and the sciatic nerve.

The 5-HT2A receptor is mainly expressed in nociceptive sensory neurons in rat lumbar dorsal root ganglia.

Several lines of evidence indicate that peripheral 5-HT2A receptors are involved in the development of inflammatory and neuropathic pain. However, their localization in sensory cell bodies is not accurately known. We therefore studied 5-HT2A receptor distribution in rat lumbar dorsal root ganglia using immunocytochemistry.