Publications by authors named "M Colaci"
Objectives: Systemic Sclerosis (SSc) is characterized by widespread microangiopathy and fibrosis of skin and visceral organs. Left ventricle involvement is usually subclinical, characterized by systolic and/or diastolic dysfunction. The global longitudinal strain (GLS), a validated and reliable technique for the measurement of ventricular longitudinal deformation by means of echocardiography, may detect subclinical systolic dysfunction of SSc myocardium.
View Article and Find Full Text PDFObjectives: To assess the reversibility of retinal microvascular changes in the long term and to investigate the potential links with other vascular diseases of COVID-19.
Methods: We designed a prospective multicenter observational study. Patients were enrolled from the Methuselah study cohort.
Article Synopsis
- - The study introduces "UIPAF," a term for patients with Usual Interstitial Pneumonia linked only to one aspect of "Interstitial Pneumonia with Autoimmune Features," aiming to compare its clinical outcomes with IPAF and idiopathic pulmonary fibrosis (IPF) patients.
- - A total of 110 IPF, 69 UIPAF, and 123 IPAF patients were analyzed, showing that UIPAF patients have autoimmune traits similar to IPAF but differ in certain antibody presence, with both groups having a similar rate of progression to specific autoimmune diseases.
- - Findings indicate that UIPAF shares autoimmune characteristics with IPAF, leading to suggestions that UIPAF could be reclassified, while highlighting that its management and prognosis align closely with
Objectives: We investigated the effectiveness and safety of filgotinib in a real-life multicentre cohort of rheumatoid arthritis (RA) patients.
Methods: RA patients were evaluated at baseline and after 12 and 24 weeks and were stratified based on previous treatments as biologic disease-modifying anti-rheumatic drug (bDMARD)-naive and bDMARD-insufficient responders (IR). Concomitant usage of methotrexate (MTX) and oral glucocorticoids (GC) was recorded.
A pancreatic neuroendocrine tumor (Pan-NET) is a rare neoplasm originating in the neuroendocrine system. Carcinoid syndrome occurs in approximately 19% of patients with functional Pan-NETs, typically when liver metastases occur. In this paper, we describe the case of a patient with a low-grade non-functional Pan-NET, but with a typical clinical presentation of carcinoid syndrome.
View Article and Find Full Text PDF