Thiol-mediated uptake (TMU) is thought to occur through dynamic covalent cascade exchange networks. Here we show that the cascade accounting for TMU of asparagusic acid derivatives (AspA) ends in the Golgi apparatus (G) and shifts from disulfide to thioester exchange with palmitoyl transferases as the final exchange partner. As a result, AspA combined with pH-sensitive fluoresceins, red-shifted silicon-rhodamines, or mechanosensitive flipper probes selectively labels the Golgi apparatus in fluorescence microscopy images in living and fixed cells.
View Article and Find Full Text PDFThis account briefly summarizes objectives and progress made so far with the Swiss-ERC AdG entitled Translational Dynamic Covalent Exchange Cascades (TIMEUP).
View Article and Find Full Text PDFObjectives: Visual aids (VAs) seem effective to improve doctor-patient communication. The objective was to describe how VAs are used in consultation and what French general practitioners (GPs) expect of them.
Methods: Cross-sectional study using a self-administered questionnaire among French GPs in 2019.
Background: This paper relies on data from the multilevel, sectoral discussions held among professional nursing and sociology individuals.
Purpose: To present the outcomes of a reflective process on racism in nursing education and practice in the cities of Toronto and Paris.
Method: The method used was a reflection on research conducted by eight individuals dealing with racism at distinct stages of their professional career.
This paper reports a simple method to recycle plastic-bottle and Li-ion-battery waste in one process by forming valuable coordination polymers (metal-organic frameworks, MOFs). Poly(ethylene terephthalate) from plastic bottles was depolymerized to produce an organic ligand source (terephthalate), and Li-ion batteries were dissolved as a source of metals. By mixing both dissolution solutions together, selective precipitation of an Al-based MOF, known as MIL-53 in the literature, was observed.
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