Publications by authors named "M Claeys"

Atrial functional mitral regurgitation (AFMR) is a distinct form of mitral regurgitation in patients with atrial fibrillation and heart failure with preserved ejection fraction. Its pathophysiology remains elusive, and data on exercise-related AFMR are scarce. We sought to investigate the impact of acute exercise on AFMR severity and to identify its determinants.

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Herpes simplex virus (HSV) in humans and pseudorabies virus (PRV) in pigs are both alphaherpesviruses. Plasmacytoid dendritic cells (pDCs) make part of the peripheral blood mononuclear cells (PBMCs) and are specialized in producing large amounts of antiviral type I interferon (IFN-I). IFN-I production by PBMCs in response to both HSV-1 and PRV can be virtually exclusively attributed to pDCs.

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(1) Background: early in the COVID-19 pandemic, reverse transcription polymerase chain reaction (RT-PCR) testing was limited. Assessing seroprevalence helps understand prevalence and reinfection risk. However, such data are lacking for the first epidemic wave in Belgian nursing homes.

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Article Synopsis
  • Recent guidelines advocate for quick initiation of lipid-lowering therapy (LLT) in patients with acute coronary syndromes (ACS) to achieve significant reductions in LDL cholesterol levels.
  • A European study involving 286 ACS patients evaluated the effectiveness of two LLT strategies: high-intensity statin monotherapy (mono-HIS) and a combination of high-intensity statins with ezetimibe (combo-HIS).
  • Findings showed that while LDL-c targets were met in under half of the patients, combo-HIS was linked to a significantly greater reduction in LDL-c levels compared to mono-HIS, suggesting its potential for more effective management in post-ACS care.*
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