Publications by authors named "M Ciuffi"
Article Synopsis
- - Gastric cancer (GC) is a complex and aggressive type of cancer that starts in the stomach and can spread to other organs, often becoming deadly by stage IV.
- - The study analyzed gene expression data from 719 patients to identify a specific gene signature linked to the progression from stage I to stage IV GC, focusing on factors like ECM organization and epithelial-to-mesenchymal transition (EMT).
- - The findings suggest that this gene signature could help identify stage I patients at higher risk of progression, potentially aiding in early treatment strategies, while also providing a new experimental model to study how gastric cancer spreads.
Objective: Patients with symptomatic uncomplicated diverticular disease (SUDD) may have a disrupted gut microbiota. However, current data are from small sample studies, and reported associations vary widely across studies. We aimed to profile the fecal microbiota in SUDD patients enrolled in primary care.
View Article and Find Full Text PDFArticle Synopsis
- The study focused on evaluating the prevalence of endoscopic and histological changes in elderly patients (over 65) undergoing upper endoscopy.
- Out of 1,336 patients, 31.4% had at least one macroscopic lesion, with erosive gastritis and erosive oesophagitis being the most common findings.
- The results indicated that the occurrence of endoscopic lesions was linked to male gender and alarm symptoms, while proton pump inhibitor (PPI) therapy reduced the likelihood of such lesions.
Upper Gastrointestinal Endoscopy Quality in Italy: A Nationwide Study.
J Gastrointestin Liver Dis
December 2023
Background And Aims: International guidelines advise improving esophagogastroduodenoscopy (EGD) quality in Western countries, where gastric cancer is still diagnosed in advanced stages. This nationwide study investigated some indicators for the quality of EGD performed in endoscopic centers in Italy.
Methods: Clinical, endoscopic, and procedural data of consecutive EGDs performed in one month in the participating centers were reviewed and collected in a specific database.