Publications by authors named "M Cinta Mane"

Wounds are one of the most critical clinical issues in plastic surgery repair and restoration. Conventional wound dressing materials cannot absorb enough wound exudates and shield the site from microbial infection. Also, despite their healing prowess, bioactive molecules from medicinal plants are less bioavailable at the wound sites.

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Managing wounds and accompanying consequences like exudation and microbiological infections is challenging in clinical practice. Bioactive compounds from traditional medicinal plants help heal wounds, although their bioavailability is low. This study uses sodium alginate (SA), gelatin (G), and Santalum album oil (SAL) to 3D print a polymeric hydrogel scaffold to circumvent these difficulties.

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We report herein a directing group-controlled, palladium-catalyzed, regio-, stereo-, and enantiospecific anti-carboxylation of unactivated, internal allenes enabled via the synergistic interplay of a rationally designed bidentate directing group, palladium catalyst, and a multifunctional acetate ligand. The corresponding trans allyl ester was obtained in excellent yields with exclusive δ-regioselectivity and anti-carboxypalladation stereocontrol. The acetate ligand of the palladium catalyst controls the regio-, stereo- and enantioselectivity in the desired transformation.

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Electrowetting on dielectric (EWOD) is used for non-mechanical optical beam steering (OBS) in optical communication systems. High-capacitance ion gel is used to construct an efficient electrowetting interface that facilitates dynamic OBS. This integration facilitates precise control of beam steering and data transmission efficiency in optical wireless communication systems.

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Article Synopsis
  • Parkinson's Disease (PD) is a progressive disorder affecting motor and non-motor functions, rooted in mitochondrial dysfunction leading to loss of dopaminergic neurons.
  • An E3 ubiquitin ligase, TRIM71, has been studied for its role in mitochondrial health and its connection to neuronal death under PD conditions, specifically in models exposed to toxins like rotenone and 6-OHDA.
  • The study found that TRIM71 promotes neuronal death in PD stress, as its increased presence on mitochondria adversely affects mitochondrial function and increases oxidative stress; whereas reducing TRIM71 levels improves mitochondrial health and cell survival.
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