Publications by authors named "M Christner"
Purpose: Listeria monocytogenes causes severe bacterial infections with the highest mortality rate among foodborne pathogens in Europe. Combination treatment with ampicillin and gentamicin is recommended for invasive manifestations. However, evidence to support this treatment approach remains limited due to a lack of randomised controlled trials.
View Article and Find Full Text PDFFor effective infection control measures for () and (), a reliable tool for screening and diagnosis is essential. Here, we aimed to establish and validate a multiplex PCR assay on an automated system using a dual-target approach for the detection of and differentiation between lymphogranuloma venereum (LGV) and non-LGV from genital and extra-genital specimens. Published primer/probe sets (: pmpH, cryptic plasmid; : porA, opa) were modified for the cobas 5800/6800/8800.
View Article and Find Full Text PDFArticle Synopsis
- A recent study investigated the presence of the hypertoxigenic Streptococcus pyogenes emm1 lineage M1 in invasive infections and scarlet fever cases in Germany, utilizing whole-genome sequencing.
- Out of 47 isolates analyzed from blood and tissue samples, 14 different emm types were identified, with emm1 being the most prevalent.
- The detection of all 27 SNPs characteristic for the M1 lineage in 14 of the emm1 isolates suggests this lineage may contribute to the rise in GAS infections in Germany, aligning with trends observed in other countries like the UK.