Carrier frequency and molecular basis of hemoglobinopathies among blood donors in eastern Morocco: Implications for blood donation and genetic diagnosis.

Background: Hemoglobinopathies represent the most commonly inherited autosomal recessive blood disorders in the world. The aim of this study was to determine the carrier frequency and molecular basis of hemoglobinopathies among blood donors in eastern Morocco. This is the first study of its kind for this country.

Characterizing Monoclonal Gammopathies in an East Moroccan Population: University Hospital Findings.

Background: Monoclonal gammopathies (MG) are frequent, especially among older people. This study aims to establish the features and etiologies of MG detected over seven years in the Biochemistry department of Mohammed VI University Hospital in Morocco.

Methods: The study was performed from Jan 1, 2016, to Sept 1, 2023, and involved 224 patients residing in east Morocco.

Evaluation of Sperm DNA Fragmentation Using Halosperm Technique after the Freezing-Thawing Process in Men: A Study on the Validation of the SCD Protocol.

Background: DNA fragmentation index (DFI) enhances routine semen analysis by providing valuable insights into male reproductive potential. Utilizing Halosperm test, a sperm chromatin dispersion (SCD) assay based on induced condensation. The purpose of this study was to assess sperm DNA damage both before and after freezing.

Precision matters: Repeatability and reproducibility of total PSA and homocysteine measurements in Alinity i-system.

Background: The precision of test measurements is critical in clinical diagnostics, especially for biomarkers like total PSA and homocysteine, which are essential to disease assessment. Using the CMIA approach, this study investigates the repeatability and reproducibility of these biomarkers on the Abbott Alinity system.

Methods: The present study was conducted in the clinical chemistry laboratory at Mohammed VI University Hospital of Oujda.

Comprehensive analysis of bioactive compounds in stamens extracts by HPLC-DAD: investigating antidiabetic activity via , , and molecular docking simulation.

Medicinal herbs used in traditional diabetes treatment are a rich source of anti-diabetic compounds. Pancreatic α-amylase inhibitors offer an effective strategy to reduce postprandial hyperglycemic levels via control of starch degradation. In this context, our study for the first time investigates the effect of stamens extracts on α-amylase inhibition.