Publications by authors named "M Chitsaz"
Polychlorinated dibenzo-p-dioxins and -furans (PCDD/Fs) are contaminants of concern in the New York/New Jersey Harbor and in the organisms of the Newtown Creek Superfund site, which lies within the harbor. Because PCDD/Fs are never intentionally produced, identifying their sources can be challenging. In this work, sources of PCDD/Fs to the sediment of Newtown Creek were investigated using Positive Matrix Factorization (PMF) to analyze two data sets containing data on concentrations of (1) PCDD/Fs and (2) PCDD/Fs plus polychlorinated biphenyls (PCBs).
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- - Spiradenocylindroma is a rare benign skin tumor that has characteristics similar to two other tumors, spiradenoma and cylindroma, and it usually appears on the head and neck.
- - The article focuses on the case of a 65-year-old woman who had a left adnexal mass, which was found to be a spiradenocylindroma after ultrasonography, MRI, and surgery.
- - The findings emphasize how difficult it can be to diagnose spiradenocylindroma, particularly when it appears in unusual locations, like within an ovarian teratoma.
Polychlorinated biphenyls (PCBs) are a primary contaminant of potential concern at the Newtown Creek superfund site. Measurements of PCBs in hundreds of samples of sediment (surface and cores) within Newtown Creek and at nearby reference locations were obtained from the Remedial Investigation (RI) databases. This data set was analyzed using Positive Matrix Factorization (PMF).
View Article and Find Full Text PDFThe role of TMS 12 in the staphylococcal multidrug efflux protein QacA.
J Antimicrob Chemother
June 2023
Article Synopsis
- The study focuses on a specific region in the QacA protein that is thought to play a key role in recognizing antimicrobial substances.
- Researchers altered 38 amino acid residues in QacA to analyze how these changes affected aspects like protein expression, drug resistance, and interaction with certain compounds.
- Findings revealed that certain mutations reduced resistance to drugs and highlighted the significance of specific amino acids in ensuring the protein's structural and functional integrity in transporting substrates.
Antimicrobial resistance in Neisseria gonorrhoeae has reached an alarming level, severely impacting the effective treatment of gonorrhea. Belonging to the resistance-nodulation-cell division (RND) superfamily of efflux transporters, the MtrD membrane protein of N. gonorrhoeae provides resistance to a broad range of antimicrobial compounds.
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