Publications by authors named "M Chiavetta"
: An increasing number of studies have reported liver involvement in both children and adults with celiac disease (CD). This often manifests as isolated hypertransaminasemia or hepatic steatosis (HS). The aim of this study was to define the prevalence of hypertransaminasemia and HS in a pediatric population with CD before starting a gluten-free diet (GFD) and to analyze how the introduction of a GFD could modify this condition.
View Article and Find Full Text PDFSome data suggest the existence of intestinal inflammation in patients with non-celiac wheat sensitivity (NCWS). We aimed to verify whether fecal calprotectin (FCP), a marker of intestinal inflammation, could be used to confirm this inflammatory status and to test its diagnostic performance in differentiating NCWS from irritable bowel syndrome/functional dyspepsia (IBS/FD). We conducted a multicenter study, comparing NCWS patients, diagnosed by a double-blind placebo-controlled wheat challenge, with IBS/FD subjects.
View Article and Find Full Text PDFArticle Synopsis
- * An analysis of fecal calprotectin (FCP) levels in 329 SRMI patients revealed that over half had elevated FCP values, indicating potential intestinal inflammation, particularly in those who reported symptoms.
- * While FCP showed higher levels in "lactose tolerants" and "maldigesters/intolerants," it was not effective in distinguishing between lactose tolerant and intolerant patients, suggesting an underlying allergic or inflammatory mechanism in some SRMI cases.
Article Synopsis
- - Anemia is a common issue in patients with Celiac Disease (CD) and is often linked to iron deficiency, with over half of studied patients showing signs of mild to moderate anemia.
- - A study of 159 CD patients revealed that 46% of those initially anemic continued to have anemia even after following a strict gluten-free diet (GFD) for one year.
- - Factors like being female, having a lower body mass index (BMI), experiencing heavy menstrual bleeding, and having low ferritin levels were associated with persistent anemia, suggesting that some cases may stem from iron loss rather than malabsorption.
Background And Aims: A wheat-free diet (WFD) represents the elective treatment for Non-celiac Wheat Sensitivity (NCWS) patients. Preliminary reports have shown a possible better tolerability of ancient grains in these subjects. The aim of this observational study was to evaluate the frequency of consumption of ancient grains and its correlation with clinical manifestations in NCWS patients.
View Article and Find Full Text PDF