Publications by authors named "M Charakida"
Article Synopsis
- The study aimed to analyze differences in maternal vascular health and blood flow parameters among three groups of pregnant women: those with gestational diabetes mellitus (GDM), those with pre-existing diabetes mellitus (DM), and those without diabetes.
- It involved a large sample of 6,350 women to gather data on various cardiovascular measurements at 35-37 weeks of gestation, noting that a significant portion of women with GDM were treated with diet, metformin, or insulin.
- Findings revealed that women with GDM and pre-existing DM had higher cardiac output, heart rate, and blood pressure compared to those without diabetes, while treatment types within the GDM group mainly affected heart rate.
Background: Hypertensive disorders of pregnancy and gestational diabetes mellitus are characterized by vascular dysfunction and are associated with long term cardiovascular risks.
Objective: This study aimed to compare different markers of maternal vascular function in women with gestational diabetes mellitus, preeclampsia, or gestational hypertension and in women whose pregnancies were unaffected by these complications and to assess the association between maternal vascular function and markers of placental perfusion and maternal vascular-placental axis in 4 groups of women.
Study Design: This was a prospective observational study of women who had routine hospital visits at 35 0/7 to 36 6/7 weeks of gestation at King's College Hospital, London, United Kingdom.
Article Synopsis
- This study examines the relationship between the peak systolic velocity ratio of the ophthalmic artery in pregnant women and the development of gestational diabetes mellitus (GDM) or preeclampsia during pregnancy.
- It involved a prospective observational analysis of nearly 4,000 women at 11 to 13 weeks' gestation, focusing on factors like maternal characteristics, medical history, and arterial flow velocity.
- Results showed that the peak systolic velocity ratio was significantly higher in women who developed GDM compared to those with unaffected pregnancies and those who developed preeclampsia, indicating potential early detection of these conditions.
Maternal vascular indices at 36 weeks' gestation in pregnancy with small or growth-restricted fetus.
Ultrasound Obstet Gynecol
October 2024
Objective: To compare maternal vascular indices and hemodynamic parameters at 35-37 weeks' gestation in pregnancies complicated by delivery of a small-for-gestational-age (SGA) or growth-restricted (FGR) neonate.
Methods: This was a prospective observational study of women with a singleton pregnancy attending for a routine hospital visit at 35 + 0 to 36 + 6 weeks' gestation. The visit included recording of maternal demographic characteristics, medical history, vascular indices and hemodynamic parameters, which were obtained using a non-invasive operator-independent device and included pulse-wave velocity, augmentation index, cardiac output, stroke volume, central systolic and diastolic blood pressure, total peripheral resistance and heart rate.