Publications by authors named "M Chabior"
Phase-contrast x-ray computed tomography (PCCT) is currently investigated as an interesting extension of conventional CT, providing high soft-tissue contrast even if examining weakly absorbing specimen. Until now, the potential for dose reduction was thought to be limited compared to attenuation CT, since meaningful phase retrieval fails for scans with very low photon counts when using the conventional phase retrieval method via phase stepping. In this work, we examine the statistical behaviour of the reverse projection method, an alternative phase retrieval approach and compare the results to the conventional phase retrieval technique.
View Article and Find Full Text PDFBreast microcalcifications play an essential role in the detection and evaluation of early breast cancer in clinical diagnostics. However, in digital mammography, microcalcifications are merely graded with respect to their global appearance within the mammogram, while their interior microstructure remains spatially unresolved and therefore not considered in cancer risk stratification. In this article, we exploit the sub-pixel resolution sensitivity of X-ray dark-field contrast for clinical microcalcification assessment.
View Article and Find Full Text PDFArticle Synopsis
- X-ray phase-contrast imaging enhances contrast and sensitivity in microtomography by depicting the real part of a specimen's complex refractive index.
- A comparative study uses data from two methods: grating-based interferometry and propagation-based phase contrast with single-distance phase retrieval, specifically on a non-homogeneous sample.
- Results indicate that grating-based interferometry is better for managing density gradients, highlighting how both techniques can complement each other in practical uses.
Objectives: Conventional X-ray attenuation-based contrast is inherently low for the soft-tissue components of the female breast. To overcome this limitation, we investigate the diagnostic merits arising from dark-field mammography by means of certain tumour structures enclosed within freshly dissected mastectomy samples.
Methods: We performed grating-based absorption, absolute phase and dark-field mammography of three freshly dissected mastectomy samples containing bi- and multifocal carcinoma using a compact, laboratory Talbot-Lau interferometer.