Publications by authors named "M Cesarone"

Background: Centellicum, a standardized Centella Asiatica extract, has been used orally for fibrosis and scar prevention. The main aim of this 2-month registry pilot study was the reduction of visible, significant scars and keloids after suturing traumatic wounds with irregular edges (lacerations), using Centellicum.

Methods: The effects of oral Centellicum (450 mg/day; 2 capsules) and a standard management (SM) on wound healing were compared with the effects of a control group that used only the standard management.

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Background: The aim of this supplement registry study was to evaluate the efficacy of Pycnogenol in controlling signs and symptoms of chronic venous insufficiency (CVI), diabetic microangiopathy and microcirculatory parameters - in diabetic patients with CVI and microangiopathy. These CVI patients are eligible for medical procedures as their incompetent superficial veins can be treated with repeated sclerotherapy and or local surgery according to needs.

Methods: During this registry study, only non-interventional managements were used.

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Background: The aim of this registry study was to evaluate the effects of Pycnogenol and Centellicum (PYCE) on skin perfusion and skin elasticity in healthy women over a period of 4 weeks.

Methods: The supplemented women used 150 mg of Pycnogenol and 450 mg of Centellicum daily. The supplemented group used the combination PYCE daily for 4 weeks and followed the standard management (SM) in addition.

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Background: The aim of this 4-week pilot registry, supplement study was to assess the effects of Pycnogenol compared to a standard management on hand osteoarthritis associated with pain. As Pycnogenol decreases inflammation and pain, chronic use of drugs, causing side effects may be reduced.

Methods: The registry patients included suffered finger pain associated with hand osteoarthritis All subjects used a standard management (SM).

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