Publications by authors named "M Ceresoli"

Background: Randomised controlled trials (RCTs) have found antibiotics to be a feasible and safe alternative to appendicectomy in adults with imaging-confirmed acute appendicitis. However, patient inclusion criteria and outcome definitions vary greatly between RCTs. We aimed to compare antibiotics with appendicectomy for the treatment of acute appendicitis using individual patient data and uniform outcome definitions.

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Purpose: Acute appendicitis during pregnancy poses unique challenges due to altered anatomical and physiological dynamics and concern about foetal well-being. This study aimed to assess management strategies and outcomes of acute appendicitis during pregnancy, focusing on non-operative management versus surgical intervention.

Methods: The study is based on the computerized healthcare utilization database of Lombardy.

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Article Synopsis
  • - Acute appendicitis is a common surgical emergency characterized by right lower quadrant abdominal pain, more frequently observed in men than in women of childbearing age, and can be diagnosed using various imaging techniques like ultrasound and CT scans.
  • - Management depends on whether the appendicitis is uncomplicated or complicated; uncomplicated cases may be treated with antibiotics, while complicated cases require surgical intervention, especially for patients with abscesses.
  • - Special considerations are needed for certain groups (like pregnant or immunosuppressed patients) who should receive timely surgical treatment to minimize complications.
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Article Synopsis
  • * A thorough literature review led to the selection of 287 studies, which informed the development of 39 key statements addressing surgical indications, timing, and techniques for SSRF.
  • * The consensus document serves to clarify best practices in managing rib fractures, helping clinicians make informed decisions about the surgical treatment process.
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