Publications by authors named "M Cerbon"

Article Synopsis
  • Viral hepatitis (A-E) is a significant global health issue, prompting the WHO to launch a 2015 initiative aimed at drastically reducing infections and deaths by 2030, especially in countries like Mexico which is among the 38 focus nations.
  • In Mexico, while there are established programs for diagnosing and treating hepatitis B and C, there is a lack of routine diagnosis for hepatitis D and E, and the National Hepatitis C Elimination Program started in 2020 has not expanded to cover hepatitis B and E.
  • Efforts to control viral hepatitis in Mexico need more resources, improved diagnosis and vaccination for hepatitis A and B, treatment coverage for hepatitis B and C, and collaboration across different sectors to enhance patient care.
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It is well known that oocytes are produced during fetal development and that the total number of primary follicles is determined at birth. In humans, there is a constant loss of follicles after birth until about two years of age. The number of follicles is preserved until the resumption of meiosis at puberty and there is no renewal of the oocytes; this dogma was maintained in the last century because there were no suitable techniques to detect and obtain stem cells.

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Viral hepatitis is the main cause of infectious liver disease. During pregnancy, a risk of vertical transmission exists both during gestation and at birth. HAV, HBV, and HCV might progress similarly in pregnant and non-pregnant women.

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Unlabelled: Glucotoxicity may exert its deleterious effects on pancreatic β-cell function via a myriad of mechanisms, leading to impaired insulin secretion and, eventually, type 2 diabetes. β-cell communication requires gap junction channels to be present among these cells. Gap junctions are constituted by transmembrane proteins of the connexins (Cxs) family.

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Obesity is associated with a low-grade chronic inflammatory process characterized by higher circulating TNFα levels, thus contributing to insulin resistance. This study evaluated the effect of silybin, the main bioactive component of silymarin, which has anti-inflammatory properties, on TNFα levels and its impact on glucose uptake in the adipocyte cell line 3T3-L1 challenged with two different inflammatory stimuli, TNFα or lipopolysaccharide (LPS). Silybin's pre-treatment effect was evaluated in adipocytes pre-incubated with silybin (30 or 80 µM) before challenging with the inflammatory stimuli (TNFα or LPS).

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