Bromodomain and extra-terminal domain (BET) proteins are therapeutic targets in several cancers including the most common malignant adult brain tumor glioblastoma (GBM). Multiple small molecule inhibitors of BET proteins have been utilized in preclinical and clinical studies. Unfortunately, BET inhibitors have not shown efficacy in clinical trials enrolling GBM patients.
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October 2024
This study aimed to compare the between-session reliability of performance and asymmetry variables between unilateral and bilateral standing broad jumps (SBJ). Twenty-four amateur basketball players (12 males and females) completed two identical sessions which consisted of four unilateral SBJs (two with each leg) and two bilateral SBJs. Mean and peak values of force, velocity and power, and impulse were obtained separately for each leg using a dual force platform.
View Article and Find Full Text PDFThis study explored the impact of different frequencies of knowledge of results (KR) on velocity performance during ballistic training. Fifteen males completed four identical sessions (three sets of six repetitions at 30% one-repetition maximum during the countermovement jump and bench press throw) with the only difference of the KR condition provided: no feedback, velocity feedback after the first half of repetitions of each set (HalfKR), velocity feedback immediately after each repetition (ImKR), and feedback of the average velocity of each set (AvgKR). When compared with the control condition, the ImKR reported the highest velocity performance (1.
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