Publications by authors named "M Cazemier"
Objective: In acromegaly, overproduction of GH and IGF-I causes abnormal extracellular matrix regulation. We hypothesized that this may predispose to the development of colonic diverticula. Because the relation between acromegaly and colonic diverticula is unknown, the study aim was to assess the prevalence of colonic diverticula in patients with cured acromegaly.
View Article and Find Full Text PDFObjective: The aim of the study was to evaluate the impact of the genomic deletion of exon 3 of the GH receptor (d3GHR) on long-term clinical outcome of acromegaly in a well-characterized cohort of patients with long-term remission of acromegaly.
Design: We conducted a cross-sectional study.
Methods: The presence of the d3GHR polymorphism was assessed in 86 acromegalic patients with long-term disease control and related to anthropometric parameters, cardiovascular risk factors, osteoarthritis, bone mineral density, colonic polyps and diverticulae, and dolichocolon.
Aim: To describe the characteristics of Dutch patients with chronic inflammatory bowel disease (IBD) first diagnosed above 60 years of age-a disease also known as old-age colitis (OAC) and to highlight a condition that has a similar appearance to IBD, namely segmental colitis associated with diverticular disease (SCAD).
Methods: A retrospective longitudinal survey of patient demographic and clinical characteristics, disease characteristics, diagnostic methods, management and course of disease was performed. The median follow-up period was 10 years.
Article Synopsis
- The study assessed the use of anal plugs and retrograde colonic irrigation (RCI) in treating fecal incontinence and constipation from 1980 to 2005.
- About 50% of the 201 patients responded; a majority found RCI more effective and were satisfied, with younger adults showing higher satisfaction rates.
- The results indicate that RCI is preferred over anal plugs, particularly among younger patients, while anal plugs can be used occasionally, especially for children.
Elastic band ligation of hemorrhoids: flexible gastroscope or rigid proctoscope?
World J Gastroenterol
January 2007
Aim: To compare rigid proctoscope and flexible endoscope for elastic band ligation of internal hemorrhoids.
Methods: Patients between 18 and 80 years old, with chronic complaints (blood loss, pain, itching or prolapse) of internal hemorrhoids of grade 1-3, were randomized to elastic band ligation by rigid proctoscope or flexible endoscope (preloaded with 7 bands). Patients were re-treated every 6 wk until the cessation of complaints.