Publications by authors named "M Caullery"

Article Synopsis
  • Organ preservation protocols combining chemoradiotherapy are effective for bladder cancer but require careful consideration of bladder volume changes during radiation.
  • Image-guided radiation therapy (IGRT), particularly using cone-beam CT with anisotropic margins, is essential for accurately targeting tumor areas and minimizing side effects.
  • Techniques like cine-MRI and adaptive radiation therapy help account for bladder changes, while protocols addressing hydration and diet can further stabilize bladder size during treatment.
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CyberKnife stereotactic body radiation therapy is used to treat extracranial tumour sites that move with respiration. It has also been employed for the successful treatment of prostate cancer, using the image-tracking CyberKnife system to compensate for intrafraction movements resulting from peristaltic motion and bladder filling. Large sporadic motions can be compensated for using an online target motion monitoring and cybernetic correction strategy.

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Radical cystectomy is the treatment of choice for nonmetastatic, muscle-infiltrating bladder cancer. However, bladder-sparing approaches can be discussed in carefully selected patients. Bladder-preservation protocols aim to guaranty local control and survival with a functional bladder and a good quality of life.

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