[Volume-effect and radiotherapy [II]. Part II: volume-effect and normal tissue].

The first part of our work has focused on the relationship between tumor volume and tumor control. Indeed, it is well known that the importance of irradiated volume could be a main parameter of radiation-induced complications. Numerous mathematical models have described the correlation between the irradiated volume and the risk of adverse effects.

[Volume-effect in radiation therapy part one: volume-effect and tumour].

Volume is an important parameter of radiation therapy. Local control is inversely related to tumor size and the complication rate increases with the importance of the irradiated volume. Although the effect of irradiated volume has been widely reported since the beginning of radiotherapy, it has been less studied than other radiation parameters such as dose, fractionation, or treatment duration.

[Conformal therapy of locally advanced cholangiocarcinoma of the main bile ducts].

Purpose: Retrospective study of 23 patients treated with conformal radiotherapy for a locally advanced bile duct carcinoma.

Patients And Methods: Eight cases were irradiated after a radical resection (R0), because they were N+; seven after microscopically incomplete resection (R1); seven were not resected (R2). A dose of 45 of 50 Gy was delivered, followed by a boost up to 60 Gy in R1 and R2 groups.

[Target volume in radiotherapy of gastric adenocarcinoma].

Unlabelled: The spread of gastric adenocarcinoma may follow three main patterns: hematogenic, lymphatic and intraperitoneal. A GTV should be considered in preoperative or exclusive radiation therapy. After non-radical surgery, a "residual GTV" will be defined with the help of the surgeon.

Preoperative radiochemotherapy and sphincter-saving resection for T3 carcinomas of the lower third of the rectum.

Objective: To evaluate the complications and oncologic and functional results of preoperative radiochemotherapy and sphincter-saving resection for T3 cancers of the lower third of the rectum.

Summary Background Data: Carcinomas of the lower third of the rectum (i.e.