Publications by authors named "M Cattral"

Purpose Of Review: Despite technical and therapeutic advances, only 20-40% of patients with colorectal liver metastases (CRLM) have resectable disease. Historically, the remaining patients with unresectable, liver-only CRLM would receive palliative chemotherapy, with a median survival of 8 months.

Recent Findings: Liver transplantation has emerged as a viable option for selected patients with CRLM.

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This study aims to identify and categorize nonmedical barriers encountered by recipients, donors, and health care providers in the context of living donor liver transplantation (LDLT). Liver transplantation is vital for individuals with liver failure, yet high mortality rates on the transplant waitlist persist. LDLT was introduced to address deceased donor organ shortages; however, its adoption varies widely across regions, prompting the need to explore barriers hindering its implementation.

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Article Synopsis
  • Living donor liver transplantation (LDLT) significantly improves survival rates for liver disease patients and decreases wait times for transplants.
  • A study of 7,257 LDLT recipients showed a median overall survival of 17 years, with various factors influencing mortality rates identified over time.
  • The findings suggest that LDLT is a safe and effective procedure, and survival rates have improved even as patient risk factors have increased, indicating room for further advancements in the field.
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Objective: Assess the impact of having a living donor on waitlist outcomes and overall survival through an intention-to-treat analysis.

Background: Living-donor liver transplantation (LDLT) offers an alternative to deceased donation in the face of organ shortage. An as-treated analysis revealed that undergoing LDLT, compared to staying on the waiting list, is associated with improved survival, even at Model for End-stage Liver Disease-sodium (MELD-Na) score of 11.

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Living liver donation (LLD) has been suggested as a potential solution to reduce the waitlist mortality for liver transplantation (LT) recipients by facilitating living donor liver transplantation (LDLT). Ensuring both donor and recipient safety is a critical aspect of LDLT. An accurate understanding of the complexity and extend of safety outcomes of the donor is imperative to maintain the high-quality standard this medical program requires.

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