Publications by authors named "M Carrere"
Background: Brain tumors are the deadliest solid tumors in children and adolescents. Most of these tumors are glial in origin and exhibit strong heterogeneity, hampering the development of effective therapeutic strategies. In the past decades, patient-derived tumor organoids (PDT-O) have emerged as powerful tools for modeling tumoral cell diversity and dynamics, and they could then help defining new therapeutic options for pediatric brain tumors.
View Article and Find Full Text PDFBackground: High-grade adult-type diffuse gliomas (HGGs) constitute a heterogeneous group of aggressive tumors that are mostly incurable. Recent advances highlighting the contribution of ribosomes to cancer development have offered new clinical perspectives. Here, we uncovered that isocitrate dehydrogenase (IDH)wt and IDHmut HGGs display distinct alterations of ribosome biology, in terms of rRNA epitranscriptomics and ribosome biogenesis, which could constitute novel hallmarks that can be exploited for the management of these pathologies.
View Article and Find Full Text PDFIn France, the horsemeat market has been declining for about 50 years and has become a specialized market. Our study aims to understand this decline with regard to the drivers and practices of consumers and non-consumers of this meat, in order to estimate the potential for this market development. To study horsemeat consumption, we analyze two sets of data: two large-scale surveys carried out on the French general population, and one ad-hoc survey focusing more specifically on the representations of horses and horsemeat.
View Article and Find Full Text PDFArticle Synopsis
- A cross-sectional study aimed to identify the motivations behind non-vegetarians reducing meat consumption and increasing legume intake in a large cohort of 25,393 French participants, mostly women around 55 years old.
- The study focused on various change-inducing motives such as health, taste, and environmental concerns, finding that health and nutrition were the strongest drivers for reducing meat while taste preferences influenced legume consumption.
- Results indicated a correlation between specific motives and individual characteristics, revealing that people motivated by health and nutrition were more likely to change their eating habits.
Article Synopsis
- * The trial included three groups: obese adolescents with and without vitamin D supplementation and a control group of normal-weight teens, finding high vitamin D insufficiency in the obese group compared to controls.
- * After 12 weeks, while vitamin D levels increased in both obese groups, improvements in intima-media thickness (IMT) were observed in the obese group receiving supplementation, although carotid compliance showed no significant change.