Publications by authors named "M Carmen Turrientes"
Prevalence, incidence and risk factors for acquisition and colonization of extended-spectrum beta-lactamase- and carbapenemase-producing Enterobacteriaceae from dogs attended at a veterinary hospital in Spain.
Comp Immunol Microbiol Infect Dis
January 2023
Article Synopsis
- Over the last decade, antibiotic resistance has risen in bacteria from companion animals, notably with strains like ESBL and CPE in pets like dogs.
- A study assessed 44 hospitalized dogs and found that 25% were colonized by ESBL-E bacteria upon admission, increasing to 45.5% at discharge, identifying specific resistant species like E. coli and K. pneumoniae.
- Factors such as prior corticosteroid use and existing health conditions were linked to higher rates of colonization, highlighting the potential risk of pets serving as reservoirs for resistant bacteria that could affect humans.
Article Synopsis
- Carbapenems are essential antibiotics but are losing effectiveness due to metallo-β-lactamases (MBLs), which are enzymes that break them down.
- Researchers discovered indole-2-carboxylates (InCs) as new inhibitors that can effectively target MBLs, maintaining activity against all major clinically relevant classes of these enzymes.
- In laboratory tests, InCs not only restored the effectiveness of carbapenems against drug-resistant Gram-negative bacteria but also demonstrated a good safety profile and strong efficacy when combined with the antibiotic meropenem in animal models of infection.
Epidemiology of the colonization and acquisition of methicillin-resistant staphylococci and vancomycin-resistant enterococci in dogs hospitalized in a clinic veterinary hospital in Spain.
Comp Immunol Microbiol Infect Dis
October 2020
Antibiotic resistance is one of the biggest threats to human and animal health. Methicillin-resistant Staphylococcus spp. (MRS) and vancomycin-resistant Enterococcus spp.
View Article and Find Full Text PDFBackground: The ST131 Escherichia coli clone is associated with the global dissemination of ESBLs. It has been hypothesized that ST131 could take advantage of better colonizing abilities. However, the data on colonization prevalence of ESBL-ST131 in European hospitals are scarce.
View Article and Find Full Text PDFPrevalence of extended-spectrum β-lactamases (ESBL) and/or carbapenemase-producing Enterobacteriaceae (EPE and CPE) in stool samples from 75 travellers, 8 people visiting friends and relatives and 3 immigrants who had travelled or came from tropical or subtropical areas was determined. Thirty-one per cent (27/86) of the subjects were faecal carriers of EPE, and 37 EPE isolates were recovered (36 Escherichia coli, 1 Klebsiella pneumoniae). CTX-M-15 was the most prevalent enzyme (64.
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