Publications by authors named "M Carmen Gonzalez-Dominguez"
Article Synopsis
- The study examines how social restrictions and different variants, specifically Alpha, Delta, and Omicron-BA.1, affected the spread of SARS-CoV-2 in Galicia, Spain.
- Using genomic data and mobility statistics, the research found that initial variant introductions mostly came from other Spanish regions and France, later shifting to include imports from Portugal and the U.S.
- Despite the number of introductions, most did not contribute significantly to the pandemic's evolution in Galicia, but major coastal cities were identified as key areas for viral transmission.
Background: The Work Ability Index (WAI) is an instrument that measures work ability. The wide dispersion of the WAI internationally has led to its adaptation for use in different countries. This study aimed to evaluate the psychometric properties of the Spanish version of the WAI.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates how social restrictions and different variants, specifically Alpha, Delta, and Omicron, affected SARS-CoV-2 transmission in Galicia, Spain.
- Using genomic data and mobility information, the research shows that the Alpha variant initially spread from other Spanish regions and France, while later variants saw increased influences from Portugal and the USA.
- Key coastal cities in Galicia were identified as significant hubs for the virus's dissemination, underscoring the importance of regional connectivity for public health strategies.
Alteplase (rtPA) remains the standard thrombolytic drug for acute ischemic stroke. However, new rtPA-derived molecules, such as tenecteplase (TNK), with prolonged half-lives following a single administration, have been developed. Although TNK is currently under clinical evaluation, the limited preclinical data highlight the need for additional studies to elucidate its benefits.
View Article and Find Full Text PDFOvariectomy, involving the surgical removal of ovaries, and estradiol replacement facilitate the understanding of sexual dimorphism-related physiological changes, encompassing reproductive biology, metabolism, and hormone-related diseases. In this study, we present a protocol for conducting ovariectomy and estradiol replacement in mice. We describe steps for performing sham and ovariectomy operations, outline preoperative preparations, and provide details on postoperative care, including analgesia administration and the removal of surgical clips.
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