Publications by authors named "M Carl"
It is known that ultrashort echo time (UTE) magnetic resonance imaging (MRI) sequences can detect signals from water protons but not collagen protons in short T2 species such as cortical bone and tendons. However, whether collagen protons are visible with the zero echo time (ZTE) MRI sequence is still unclear. In this study, we investigated the potential of the ZTE MRI sequence on a clinical 3T scanner to directly image collagen protons via DO exchange and freeze-drying experiments.
View Article and Find Full Text PDFAcetylcholine (ACh), a vital neurotransmitter for both the peripheral (PNS) and central nervous systems (CNS), signals through nicotinic ACh receptors (nAChRs) and muscarinic ACh receptors (mAChR). Here, we explore the expression patterns of three nAChR subunits, chrna3, chrnb4, and chrna5, which are located in an evolutionary conserved cluster. This close genomic positioning, in a range of vertebrates, may indicate co-functionality and/or co-expression.
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- The study aimed to compare the image quality and visibility of lesions in zero echo time (ZTE) MRI using a deep learning (DL) algorithm against conventional reconstruction methods, and to evaluate DL ZTE's effectiveness in assessing bone loss for shoulder instability compared to CT scans.
- Forty-four patients with shoulder instability underwent both ZTE MRI and CT scans, with images evaluated by two radiologists for clarity, resolution, and how well they showed lesions, using a rating scale.
- Results indicated that DL ZTE MRI images had superior resolution and showed lesions more clearly than conventional methods, with excellent agreement between DL ZTE and CT scans for measuring bone parameters.
Purpose: To develop a novel imaging sequence that independently acquires water and fat images while being inherently insensitive to motion.
Methods: The new sequence, termed spectrally selective and interleaved water imaging and fat imaging (siWIFI), uses a narrow bandwidth RF pulse for selective excitation of water and fat separately. The interleaved acquisition method ensures that the obtained water and fat images are inherently coregistered.
Evaluation of 3D bone morphology of the glenohumeral joint is necessary for pre-surgical planning. Zero echo time (ZTE) magnetic resonance imaging (MRI) provides excellent bone contrast and can potentially be used in place of computed tomography. Segmentation of shoulder anatomy, particularly humeral head and acetabulum, is needed for detailed assessment of each anatomy and for pre-surgical preparation.
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