Publications by authors named "M Carena"
Article Synopsis
- Visceral obesity increases cardiovascular risk, including heart failure, prompting a study on the role of microRNAs (miRNAs) from epicardial adipose tissue (EAT) in regulating heart function and outcomes.
- Researchers identified that EAT miR-92a-3p lowers oxidative stress in the heart and is linked to reduced cardiovascular events, showing its role in the heart's redox state via a specific biological pathway.
- The study suggests that EAT-derived miR-92a-3p could be a promising therapeutic target for preventing and treating heart disease associated with obesity.
Quantum simulations of lattice gauge theories for the foreseeable future will be hampered by limited resources. The historical success of improved lattice actions in classical simulations strongly suggests that Hamiltonians with improved discretization errors will reduce quantum resources, i.e.
View Article and Find Full Text PDFDrought currently affects several regions worldwide and tends to be more frequent due to climate change. It might compromise food security and the economic structure related to agribusiness. Popcorn has a crucial role in the Brazilian economy, but the cultivars that adapt to water stress, the most prejudicial abiotic stress for crop productivity, are unknown to date.
View Article and Find Full Text PDFArticle Synopsis
- This study examines how canagliflozin, an SGLT2 inhibitor, impacts heart function and potentially improves cardiovascular outcomes for heart failure patients through effects on redox signaling.!
- Researchers conducted multiple studies, involving patient biopsies and cell cultures, to see how this drug influences oxidative stress and inflammation in heart tissue, finding that it reduces harmful enzyme activity while enhancing protective mechanisms.!
- The results suggest that canagliflozin operates through SGLT1/AMPK/Rac1 signaling, leading to reduced inflammation and cell death in heart muscle cells, uncovering a new mechanism behind its positive cardiac effects.!