Publications by authors named "M Campello"
Article Synopsis
- Spine disorders are a major global disability issue, highlighting the need for improved access to high-quality spine care to foster social inclusion and dignity for affected individuals.
- SPINE20 outlines six recommendations for G20 countries, including providing evidence-based education for health workers, affordable spine care interventions, and investing in health policy research to support rehabilitation integration.
- Emphasizing the importance of social equity, SPINE20 urges collaborations among healthcare providers and policymakers to ensure comprehensive access to spine care, ultimately aiming to enhance population well-being and productivity.
Article Synopsis
- The study details the creation of an iodine-labeled acridine orange compound ([I]-C) designed to bind G-quadruplexes, with a focus on its potential use in Auger Electron Radiopharmaceutical Therapy (AE-RPT) for treating cervical cancer.
- [I]-C showed significant cellular uptake in HeLa cervical cancer cells, leading to reduced cell viability and severe DNA damage likely caused by the emitted Auger Electrons from iodine.
- Although [I]-C exhibited fast clearance from the bloodstream and good stability, it had poor tumor uptake; combining it with the AS1411 aptamer improved blood retention but did not enhance tumor targeting, suggesting that new delivery methods need to
Introduction: Musculoskeletal injuries (MSIs) pose a significant problem for active duty service members (ADSMs). MSIs may compromise readiness and are one of the main reasons for separation from the Navy and long-term disability. Implementation of optimal treatment strategies rests on understanding the characteristics of MSI complaints in a given population.
View Article and Find Full Text PDFIntroduction: Musculoskeletal injuries (MSIs) are a leading cause of separation from the U.S. Navy.
View Article and Find Full Text PDFThe present work consisted of an exploratory study aiming to evaluate in vitro the potential of AuNPs during Radiation Therapy (RT) in human pancreatic adenocarcinoma cells. AuNPs coated with hyaluronic and oleic acids (HAOA-AuNPs) or with bombesin peptides (BBN-AuNPs) were used. AuNPs were characterized by Atomic Force Microscopy (AFM) and Dynamic Light Scattering.
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